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Peptide regulation of ageing Introduction For many years a phenomenon of ageing had been studied within the framework of ethics and social issues. Only in the last century the society realized that a process of ageing should be studied from a different viewpoint, that is, as a special physiologic mechanism bearing a certain evolutionary significance. Ageing is the most complicate issue in medicine and biology. The process of ageing is a gradual involution of tissues and development of organism malfunctioning. Its symptoms appear already at the end of the reproductive period and become more pronounced with ageing. At the end of the XIX century I.I. Metchnikov showed that enhancement of cellular immunity contributed to a lifespan increase. He developed a phagocytic theory of immunity and considered human organism capable of combating pathologic ageing [1]. In 1908 he was awarded the Nobel Prize in Physiology or Medicine together with Paul Ehrlich. And only one century later, Peter Doherty and Rolf Zinkernagel conducted detailed studies in specificity of cellular immunity in case of viral infection (the Nobel Prize in Physiology or Medicine 1996)
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